hykim11@snu.ac.kr (+82)02-740-8970

Welcome to Laboratory of Mucosal Immunology

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Mucosal Immunology?

Mucosal immunology is the study of immune responses that occur at mucosal surfaces, such as the intestines, the urogenital tract and the lungs. These tissues are closely associated with the external environment and the mucosal immune system must provide protective immunity to pathogens but remain tolerant of non-harmful environmental substances.

Our Publications

Our researchers are posting research related to mucosal immunology in various international journals. If you want to read our paper, please check the Publication section on the page.

About us

We are made up of researchers who belong to Seoul National University, department of biomedical sciences. For more information, see the information at the bottom of the page.

Image Gallery

Photos taken at various events such as lab events and international conferences are posted on the homepage.

Research Interest

The major research interests of the lab are related to host defense and innate immune responses in the mucosal tissues such as lung, skin, and gut. We are trying to understand how innate immune circuits detect and respond to allergen/microbe challenges in the mucosal tissue and how innate immune circuit contribute to tissue homeostasis or harmful inflammatory responses in the mucosal tissues.We are interested in defining the functions of Innate lymphoid cells(ILCs), which are a group of lymphocytes that lack specific antigen receptors. We investigate the role of ILCs in animal models of various disease such as asthma, atopic dermatitis, and colitis. We also try to translate the data in human pathology by testing various human samples, and to find the potential role of ILCs in diagnosis, as biomarkers and/or as future treatment targets

Research Themes

1. Induction and regulation of innate immune cells in the mucosal tissue 2. ILCs-immune cell interactions in various disease 3. Epigenetic control of activation or inhibition of ILCs 4. Finding potential biomarker of allergic disease 5. Host-immune cell-microbiome interaction

Members

Publications

Alumni

Since

Publications

You can examine recently published documentations...

De novo fatty-acid synthesis protects invariant NKT cells from cell death, thereby promoting their homeostasis and pathogenic roles in airway hyperresponsiveness

Jaemoon Koh, Yeon Duk Woo, Hyun Jung Yoo, Jun-Pyo Choi, Sae Hoon Kim, Yoon-Seok Chang, Kyeong Cheon Jung, Ji Hyung Kim, Yoon Kyung Jeon, Hye Young Kim, Doo Hyun Chung


eLife

The protective roles of integrin α4β7 and Amphiregulin-expressing innate lymphoid cells in lupus nephritis

Seungwon Ryu, Kyung Ah Kim, Jinwoo Kim, Dong Hun Lee, Yong-Soo Bae, Hajeong Lee, Byoung Choul Kim, Hye Young Kim


Cell Mol Immunol

SERTAD1 initiates NLRP3-mediated inflammasome activation through restricting NLRP3 polyubiquitination

Jihoon Ha, Minbeom Kim, Jin Seok Park, Yerin Lee, Jae Young Lee, Jin-Cheol Shin, Dongyeob Seo, Seong Shil Park, Jiyeon You, Su Myung Jung, Hye Young Kim, Seiya Mizuno, Satoru Takahashi, Seong-Jin Kim, Seok Hee Park


Cell reports

Glutamyl-prolyl-tRNA synthetase (EPRS1) drives tubulointerstitial nephritis-induced fibrosis by enhancing T cell proliferation and activity

Chaelin Kang, Donghwan Yun, Haein Yoon, Minki Hong, Juhyeon Hwang , Hyun Mu Shin, Seokwoo Park , Seongmin Cheon, Dohyun Han, Kyung Chul Moon, Hye Young Kim, Eun Young Choi, Eun-Young Lee, Myung Hee Kim, Chang Wook Jeong, Cheol Kwak, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo , Dong-Sup Lee, Yon Su Kim, Seung Seok Han


Kidney International

Innate Type-2 Cytokines: From Immune Regulation to Therapeutic Targets

Hye Young Kim, Dongjin Jeong, Ji Hyung Kim, and Doo Hyun Chung


Immune network

See More...

You can see more publications on following page.

People

People of our Laboratory.

Professor

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김혜영 (Hye Young Kim)

서울대학교 의과대학 의과학과 교수

 

 학력

  • Feb.2003 - Aug.2006 Ph.D.(Immunology/Seoul National University College of Medicine)
  • Feb.2001 - Aug.2003 M.S (Genetics/Seoul National University)
  • Mar.1997- Feb.2001 B.S. (Biology/Ewha Womans University)

 

경력

  • 2021.3- 현재 Professor, Seoul National University College of Medicine
  • 2014.3-2021.2 Associate professor, Seoul National University College of Medicine
  • 2011.2-2013.7 Instructor (Research Associate), Harvard Medical School/BCH
  • 2006.10-2011.1 Research fellow, Harvard Medical School/BCH

 

학회/학술활동

  • 2021-현재 Review editor, Frontiers in Immunology
  • 2021-현재 Editorial Board Member, Molecules and cells
  • 2021-현재 Editorial Board Member, Allergy, Asthma & Immunology Research
  • 2020-현재 차세대 한림원 회원
  • 2020-현재 대한면역학회 평위원
  • 2024 대한면역학회연구위원장
  • 2022-현재 대한면역학회 국제협력위원
  • 2019-현재 생화학분자생물학회 대위원 
  • 2024 생화학분자생물학회 학술위원
  • 2024 분자세포생물학회 정책위원
  • 2024 여성생명과학 기술포럼 포상위원
  • 2022 대한면역학회 기획위원
  • 2017-2023 대한면역학회 학술위원
  • 2019-2020 수지상세포연구회 학술위원
  • 2019 생화학분자생물학회 교육실무위원
  • 2018-2019 여성생명과학 기술포럼 교육위원
  • 2016 생화학분자생물학회 홍보위원
  • 2015 분자세포생물학회 편집위원

 

수상

  • 2023 보건복지부 우수연구부분 장관표창 
  • 2023 연구업적 우수교원상(Seoul National University College of Medicine)
  • 2023 임성기재단 제2회 임성기연구자상 젊은연구자상
  • 2023 의과학연구정보센터 한국의 우수 연구자 선정 (Medical Research Information Center)
  • 2022 연구업적 우수교원상(Seoul National University College of Medicine)
  • 2022 KAI-Genexine Award(Korean Association of Immunologists)
  • 2022 한국분자세포생물학회 Blue Ribbon 연자선정
  • 2021 젊은 과학자상(Seoul National University College of Medicine)
  • 2020 연구업적 우수교원상(Seoul National University College of Medicine)
  • 2019 연구업적 우수교원상(Seoul National University College of Medicine)
  • 2016 Excellent paper award(Korean Association of Immunologists)
  • 2015 연구업적 우수교원상(Seoul National University College of Medicine)
  • 2014 L'Oréal-UNESCO Awards for Women in Science(Korea)
  • 2010 Houseofficer development award(Children’s Hospital Boston)

Members

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고영균 (Young Gyun Ko)

Combined M.S./Ph.D. Course

Interested in

  • Innate Immunity (ILCs, Macrophages)
  • Immunometabolism
  • Cancer immunology
  • Idiopathic pulmonary fibrosis
  • Pancreatitis
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공환석 (Hwanseok Gong)

Combined M.S./Ph.D. Course

Interested in

  • Muscle regeneration
  • Innate immune system
  • Mechanoimmunology
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김동모 (DongMo Kim)

Combined M.S./Ph.D. Course

Interested in

  • Immunometabolism
  • Innate immunity
  • Metabolic disorders
  • Allergic diseases
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김지현 (Jihyun Kim)

Post Doctoral Researcher

Interested in

  • Innate immunity
  • Respiratory diseases
  • Cancer Immunology
  • Innate immune memory
  • Innate-Adaptive immune crosstalk
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김진우 (Jinwoo Kim)

Combined M.S./Ph.D. Course

Interested in

  • Innate Immunity
  • Mental Disorder associated Brain ILCs
  • Autoimmune Diseases
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안유진 (Yoojin Ahn)

Combined M.S./Ph.D. Course

Interested in

  • Innate Immunity
  • SARS-CoV-2(Covid-19)
  • Histone Deacetylase
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임민영 (MinYeong Lim)

Combined M.S./Ph.D. Course

Interested in

  • Mechanoimmunology(Piezo1)
  • Stromal-Immune Cell Interaction
  • Eosinophilic Esophagitis
  • Lung Emphysema
  • SARS-CoV-2(Covid-19)
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함종호 (Jongho Ham)

Post Doctoral Researcher

Interested in

  • Immunometabolism
  • Innate immunity
  • Metabolic disorders
  • Allergic diseases
  • Tumor microenvironment
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양우석 (Yang Woo Seok)

Combined M.S./Ph. D. Course

Interested in

  • Innate Immunity
  • Immunometabolism
  • Mechanoimmunology

 

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박수현 (Park Su Hyun)

Combined M.S./Ph. D. Course

Interested in 

  • Innate immunity
  • Innate immune memory
  • Epigenetic modification

 

Alumni

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류승원 (Seungwon Ryu)

Interested in

  • Renal inflammation
  • Translational immunology

 

Current Address

  • Assistant Professor, Department of Microbiology, Gachon University College of Medicine

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신재우 (Jae Woo Shin)

Interested in

  • Allergic Diseases
  • Lung Fibrosis & Asthma
  • Epithelium-derived innate cytokines


Current Address

  • Post-Doctoral Course, La Jolla Institute for Immunology(LJI)

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장윤아 (Yuna Chang)

Interested in

  • Cancer
  • Inflammatory diseases
  • Drug discovery


Current Address

  • Professional, Drug Discovery Research Institute, LG Chem

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김민호 (Minho Kim)

Interested in

  • Immunology
  • Microbiology
  • Epidemiology

 

Certification

  • CFA Level 1, Certified Investment Manager

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고병철 (Byeongcheol Ko)

Interested in 

  • Innate Immunity
  • Allergic Diseases
  • Atopic Dermatitis

Current Address
  • Seoul National University Hospital

 

Contact

Laboratory of Mucosal Immunology

Location:

103 Daehak-ro, Jongro-gu, Seoul, Korea

Call:

(+82)02-740-8970

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