Mucosal immunology is the study of immune responses that occur at mucosal surfaces, such as the intestines, the urogenital tract and the lungs. These tissues are closely associated with the external environment and the mucosal immune system must provide protective immunity to pathogens but remain tolerant of non-harmful environmental substances.
Our researchers are posting research related to mucosal immunology in various international journals. If you want to read our paper, please check the Publication section on the page.
We are made up of researchers who belong to Seoul National University, department of biomedical sciences. For more information, see the information at the bottom of the page.
Photos taken at various events such as lab events and international conferences are posted on the homepage.
The major research interests of the lab are related to host defense and innate immune responses in the mucosal tissues such as lung, skin, and gut. We are trying to understand how innate immune circuits detect and respond to allergen/microbe challenges in the mucosal tissue and how innate immune circuit contribute to tissue homeostasis or harmful inflammatory responses in the mucosal tissues.We are interested in defining the functions of Innate lymphoid cells(ILCs), which are a group of lymphocytes that lack specific antigen receptors. We investigate the role of ILCs in animal models of various disease such as asthma, atopic dermatitis, and colitis. We also try to translate the data in human pathology by testing various human samples, and to find the potential role of ILCs in diagnosis, as biomarkers and/or as future treatment targets
1. Induction and regulation of innate immune cells in the mucosal tissue 2. ILCs-immune cell interactions in various disease 3. Epigenetic control of activation or inhibition of ILCs 4. Finding potential biomarker of allergic disease 5. Host-immune cell-microbiome interaction
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You can examine recently published documentations...
Choi G, Ju HY, Bok J, Choi J, Shin JW, Oh H, Jeon Y, Kim J, Kim D, Moon H, Lee JE, Keum YA, Kim YM, Kim HY., Park SH, Han MR, Chung YS.
Proc Natl Acad Sci U S A
Lee, J. E., Kim, M., Ochiai, S., Kim, S. H., Yeo, H., Bok, J., Kim, J., Park, M., Kim, D., Lamiable, O., Lee, M., Kim, M. J., Kim HY., Ronchese, F., Kwon, S. W., Lee, H., Kim, T. G. & Chung, Y.
Cell Reports
Sangsin Lee, Seung Geun Song, Gwanghun Kim, Sehui Kim, Hyun Jung Yoo, Jaemoon Koh, Ye-Ji Kim, Jingwen Tian, Eunji Cho, Youn Soo Choi, Sunghoe Chang, Hyun Mu Shin, Kyeong Cheon Jung, Ji Hoon Kim, Tae Min Kim, Yoon Kyung Jeon, Hye Young Kim, Minho Shong, Ji Hyung Kim, Doo Hyun Chung
Science Advances
Seungwon Ryu, Kyung Ah Kim, Jinwoo Kim, Dong Hun Lee, Yong-Soo Bae, Hajeong Lee, Byoung Choul Kim, Hye Young Kim
Cell Mol Immunol
Jihoon Ha, Minbeom Kim, Jin Seok Park, Yerin Lee, Jae Young Lee, Jin-Cheol Shin, Dongyeob Seo, Seong Shil Park, Jiyeon You, Su Myung Jung, Hye Young Kim, Seiya Mizuno, Satoru Takahashi, Seong-Jin Kim, Seok Hee Park
Cell reports
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Laboratory of Mucosal Immunology
103 Daehak-ro, Jongro-gu, Seoul, Korea
hykim11@snu.ac.kr
(+82)02-740-8970
