Laboratory of Mucosal Immunology

Publications

2025

2025

2025

Antigen Cross-Presentation by Type-2 Innate Lymphoid Cells Facilitates the Activation of Anti-Tumor CD8+ T Cells
Jihyun Kim, Seung Geun Song, Suhyun Park, Young Gyun Ko, Jongho Ham, TaeSoo Kim, Sang-Jun Ha, Yong-Soo Bae, Doo Hyun Chung, Hye Young Kim
Cancer Research

2025

Modulating the PD-1-FABP5 axis in ILC2s to regulate adipose tissue metabolism in obesity
Jongho Ham, Jaemoon Koh, Jungeun Kim, Joo-Youn Cho, TaeSoo Kim, Doo Hyun Chung, Yong-Soo Bae, Hye Young Kim
Molecular Therapy

2025

Cell-intrinsic PD-L1 signaling drives immunosuppression by myeloid-derived suppressor cells through IL-6/Jak/Stat3 in PD-L1-high lung cancer
Hyein Jeong, Jaemoon Koh, Sehui Kim, Jeemin Yim, Seung Geun Song, Hanbyeol Kim, Yingying Li, Soo Hyun Lee, Yeon Kyu Chung, Hongsoon Kim, Chul-Hwan Lee, Hye Young Kim, Bhumsuk Keam, Se-Hoon Lee, Doo Hyun Chung, Yoon Kyung Jeon
J Immunother Cancer

2025

2024

2024

NRF2 is a spatiotemporal metabolic hub essential for the polyfunctionality of Th2 cells
Choi G, Ju HY, Bok J, Choi J, Shin JW, Oh H, Jeon Y, Kim J, Kim D, Moon H, Lee JE, Keum YA, Kim YM, Kim HY., Park SH, Han MR, Chung YS.
Proc Natl Acad Sci U S A

2024

Tonic type 2 immunity is a critical tissue checkpoint controlling autoimmunity in the skin
Lee, J. E., Kim, M., Ochiai, S., Kim, S. H., Yeo, H., Bok, J., Kim, J., Park, M., Kim, D., Lamiable, O., Lee, M., Kim, M. J., Kim HY., Ronchese, F., Kwon, S. W., Lee, H., Kim, T. G. & Chung, Y.
Cell Reports

2024

CRIF1 deficiency induces FOXP3LOW inflammatory non-suppressive regulatory T cells, thereby promoting antitumor immunity
Sangsin Lee, Seung Geun Song, Gwanghun Kim, Sehui Kim, Hyun Jung Yoo, Jaemoon Koh, Ye-Ji Kim, Jingwen Tian, Eunji Cho, Youn Soo Choi, Sunghoe Chang, Hyun Mu Shin, Kyeong Cheon Jung, Ji Hoon Kim, Tae Min Kim, Yoon Kyung Jeon, Hye Young Kim, Minho Shong, Ji Hyung Kim, Doo Hyun Chung
Science Advances

2024

The protective roles of integrin α4β7 and Amphiregulin-expressing innate lymphoid cells in lupus nephritis
Seungwon Ryu, Kyung Ah Kim, Jinwoo Kim, Dong Hun Lee, Yong-Soo Bae, Hajeong Lee, Byoung Choul Kim, Hye Young Kim
Cell Mol Immunol

2024

SERTAD1 initiates NLRP3-mediated inflammasome activation through restricting NLRP3 polyubiquitination
Jihoon Ha, Minbeom Kim, Jin Seok Park, Yerin Lee, Jae Young Lee, Jin-Cheol Shin, Dongyeob Seo, Seong Shil Park, Jiyeon You, Su Myung Jung, Hye Young Kim, Seiya Mizuno, Satoru Takahashi, Seong-Jin Kim, Seok Hee Park
Cell reports

2024

Glutamyl-prolyl-tRNA synthetase (EPRS1) drives tubulointerstitial nephritis-induced fibrosis by enhancing T cell proliferation and activity
Chaelin Kang, Donghwan Yun, Haein Yoon, Minki Hong, Juhyeon Hwang , Hyun Mu Shin, Seokwoo Park , Seongmin Cheon, Dohyun Han, Kyung Chul Moon, Hye Young Kim, Eun Young Choi, Eun-Young Lee, Myung Hee Kim, Chang Wook Jeong, Cheol Kwak, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo , Dong-Sup Lee, Yon Su Kim, Seung Seok Han
Kidney International

2024

2023

JAK3 inhibitor suppresses multipotent ILC2s and attenuates steroid-resistant asthma
Jihyun Kim, Jongho Ham, Hye Ryun Kang, Yong-Soo Bae, TaeSoo Kim, Hye Young Kim
Science Advances

2023

2023

De novo fatty-acid synthesis protects invariant NKT cells from cell death, thereby promoting their homeostasis and pathogenic roles in airway hyperresponsiveness
Jaemoon Koh, Yeon Duk Woo, Hyun Jung Yoo, Jun-Pyo Choi, Sae Hoon Kim, Yoon-Seok Chang, Kyeong Cheon Jung, Ji Hyung Kim, Yoon Kyung Jeon, Hye Young Kim, Doo Hyun Chung
Elife

2023

2023

2023

Discovery of highly immunogenic spleen-resident FCGR3+CD103+ cDC1s differentiated by IL-33-primed ST2+ basophils
Myeong-Ho Kang, JungHyub Hong , Jinjoo Lee, Min-Suk Cha, Sangho Lee, Hye-Young Kim, Sang-Jun Ha, Yong Taik Lim, Yong-Soo Bae
Cell and Molecular Immunology

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