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2025
- γδ+ T-cell-derived IL-17A stimulates airway epithelial/stromal cells to secrete G-CSF, promoting lung-specific pathogenic Siglec-F+ neutrophil development in PPE-induced emphysema
- JungHyub Hong Myeong-Ho Kang Jinjoo Lee Min-Suk Cha Yoe-Sik Bae Hye Young Kim Yong Taik Lim Yong-Soo Bae
- Cell Mol Immunol
2025
- A parallel reaction monitoring-mass spectrometric method for studying lipid biosynthesis in vitro using 13C16-palmitate as an isotope tracer
- Kyeong-Seog Kim , Young Gyun Ko, Woo Seok Yang, Hye Young Kim, Joo-Youn Cho
- Analytica Chimica Acta
2025
- Antigen Cross-Presentation by Type-2 Innate Lymphoid Cells Facilitates the Activation of Anti-Tumor CD8+ T Cells
- Jihyun Kim, Seung Geun Song, Suhyun Park, Young Gyun Ko, Jongho Ham, TaeSoo Kim, Sang-Jun Ha, Yong-Soo Bae, Doo Hyun Chung, Hye Young Kim
- Cancer Research
2025
- Modulating the PD-1-FABP5 axis in ILC2s to regulate adipose tissue metabolism in obesity
- Jongho Ham, Jaemoon Koh, Jungeun Kim, Joo-Youn Cho, TaeSoo Kim, Doo Hyun Chung, Yong-Soo Bae, Hye Young Kim
- Molecular Therapy
2025
- Cell-intrinsic PD-L1 signaling drives immunosuppression by myeloid-derived suppressor cells through IL-6/Jak/Stat3 in PD-L1-high lung cancer
- Hyein Jeong, Jaemoon Koh, Sehui Kim, Jeemin Yim, Seung Geun Song, Hanbyeol Kim, Yingying Li, Soo Hyun Lee, Yeon Kyu Chung, Hongsoon Kim, Chul-Hwan Lee, Hye Young Kim, Bhumsuk Keam, Se-Hoon Lee, Doo Hyun Chung, Yoon Kyung Jeon
- J Immunother Cancer
2025
- Tissue-Specific Metabolic Reprogramming in Innate Lymphoid Cells and Its Impact on Disease
- Jongho Ham, Wooseok Yang , Hye Young Kim
- Immune Network
2024
- Esophageal ILC2s mediate abnormal epithelial remodeling in eosinophilic esophagitis via Areg-EGFR signaling
- MinYeong Lim, Taesoo Kim, Hyesung Kim, Bo Gun Jang, Jae Kyung Myung , Hye Young Kim
- Cell Mol Immunol
2024
- NRF2 is a spatiotemporal metabolic hub essential for the polyfunctionality of Th2 cells
- Choi G, Ju HY, Bok J, Choi J, Shin JW, Oh H, Jeon Y, Kim J, Kim D, Moon H, Lee JE, Keum YA, Kim YM, Kim HY., Park SH, Han MR, Chung YS.
- Proc Natl Acad Sci U S A
2024
- Tonic type 2 immunity is a critical tissue checkpoint controlling autoimmunity in the skin
- Lee, J. E., Kim, M., Ochiai, S., Kim, S. H., Yeo, H., Bok, J., Kim, J., Park, M., Kim, D., Lamiable, O., Lee, M., Kim, M. J., Kim HY., Ronchese, F., Kwon, S. W., Lee, H., Kim, T. G. & Chung, Y.
- Cell Reports
2024
- CRIF1 deficiency induces FOXP3LOW inflammatory non-suppressive regulatory T cells, thereby promoting antitumor immunity
- Sangsin Lee, Seung Geun Song, Gwanghun Kim, Sehui Kim, Hyun Jung Yoo, Jaemoon Koh, Ye-Ji Kim, Jingwen Tian, Eunji Cho, Youn Soo Choi, Sunghoe Chang, Hyun Mu Shin, Kyeong Cheon Jung, Ji Hoon Kim, Tae Min Kim, Yoon Kyung Jeon, Hye Young Kim, Minho Shong, Ji Hyung Kim, Doo Hyun Chung
- Science Advances
2024
- The protective roles of integrin α4β7 and Amphiregulin-expressing innate lymphoid cells in lupus nephritis
- Seungwon Ryu, Kyung Ah Kim, Jinwoo Kim, Dong Hun Lee, Yong-Soo Bae, Hajeong Lee, Byoung Choul Kim, Hye Young Kim
- Cell Mol Immunol
2024
- SERTAD1 initiates NLRP3-mediated inflammasome activation through restricting NLRP3 polyubiquitination
- Jihoon Ha, Minbeom Kim, Jin Seok Park, Yerin Lee, Jae Young Lee, Jin-Cheol Shin, Dongyeob Seo, Seong Shil Park, Jiyeon You, Su Myung Jung, Hye Young Kim, Seiya Mizuno, Satoru Takahashi, Seong-Jin Kim, Seok Hee Park
- Cell reports
2024
- Glutamyl-prolyl-tRNA synthetase (EPRS1) drives tubulointerstitial nephritis-induced fibrosis by enhancing T cell proliferation and activity
- Chaelin Kang, Donghwan Yun, Haein Yoon, Minki Hong, Juhyeon Hwang , Hyun Mu Shin, Seokwoo Park , Seongmin Cheon, Dohyun Han, Kyung Chul Moon, Hye Young Kim, Eun Young Choi, Eun-Young Lee, Myung Hee Kim, Chang Wook Jeong, Cheol Kwak, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo , Dong-Sup Lee, Yon Su Kim, Seung Seok Han
- Kidney International
2024
- Innate Type-2 Cytokines: From Immune Regulation to Therapeutic Targets
- Hye Young Kim, Dongjin Jeong, Ji Hyung Kim, and Doo Hyun Chung
- Immune network
2023
- JAK3 inhibitor suppresses multipotent ILC2s and attenuates steroid-resistant asthma
- Jihyun Kim, Jongho Ham, Hye Ryun Kang, Yong-Soo Bae, TaeSoo Kim, Hye Young Kim
- Science Advances
2023
- Classical monocyte-derived macrophages as therapeutic targets of umbilical cord mesenchymal stem cells: comparison of intratracheal and intravenous administration in a mouse model of pulmonary fibrosis
- Sun Mi Choi, Yosep Mo, Ji Young Bang, Young Gyun Ko, Yoon Hae Ahn, Hye Young Kim, Jaemoon Koh, Jae Joon Yim, Hye Ryun Kang
- Respiratory Research
2023
- De novo fatty-acid synthesis protects invariant NKT cells from cell death, thereby promoting their homeostasis and pathogenic roles in airway hyperresponsiveness
- Jaemoon Koh, Yeon Duk Woo, Hyun Jung Yoo, Jun-Pyo Choi, Sae Hoon Kim, Yoon-Seok Chang, Kyeong Cheon Jung, Ji Hyung Kim, Yoon Kyung Jeon, Hye Young Kim, Doo Hyun Chung
- Elife
2023
- Deciphering the complexities of mucosal innate lymphocytes: guardians and potential therapeutic targets
- Hye Young Kim, Ji Hyung Kim
- Experimental and Molecular Medicine
2023
- Versatile roles of innate lymphoid cells at the mucosal barrier: from homeostasis to pathological inflammation
- Seungwon Ryu, MinYeong Lim, Jinwoo Kim, Hye Young Kim
- Experimental and Molecular Medicine
2023
- Discovery of highly immunogenic spleen-resident FCGR3+CD103+ cDC1s differentiated by IL-33-primed ST2+ basophils
- Myeong-Ho Kang, JungHyub Hong , Jinjoo Lee, Min-Suk Cha, Sangho Lee, Hye-Young Kim, Sang-Jun Ha, Yong Taik Lim, Yong-Soo Bae
- Cell and Molecular Immunology