Laboratory of Mucosal Immunology

Publications

2017

IL-23 secreted by bronchial epithelial cells contributes to allergic sensitization in asthma model: role of IL-23 secreted by bronchial epithelial cells.
Lee Hyun Seung, Park Da-Eun, Lee Ji-Won, Chang Yuna, Kim Hye Young, Song Woo-Jung, Kang Hye-Ryun, Park Heung-Woo, Chang Yoon-Seok, Cho Sang-Heon
Am. J. Physiol. Lung Cell Mol. Physiol. 2017 1;312:L13-L21

2016

2015

Thalidomide inhibits alternative activation of macrophages in vivo and in vitro: a potential mechanism of anti-asthmatic effect of thalidomide.
Lee Hyun Seung, Kwon Hyouk-Soo, Park Da-Eun, Woo Yeon Duk, Kim Hye Young, Kim Hang-Rae, Cho Sang-Heon, Min Kyung-Up, Kang Hye-Ryun, Chang Yoon-Seok
PLoS ONE 2015 ;10:e0123094

2014

Pivotal role of IL-6 in the hyperinflammatory responses to subacute ozone in adiponectin-deficient mice.
Kasahara David I, Kim Hye Y, Mathews Joel A, Verbout Norah G, Williams Alison S, Wurmbrand Allison P, Ninin Fernanda M C, Neto Felippe L, Benedito Leandro A P, Hug Christopher, Umetsu Dale T, Shore Stephanie A
Am. J. Physiol. Lung Cell Mol. Physiol. 2014 3;306:L508-20

2014

2014

2014

2014

Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Kim Hye Young, Lee Hyun Jun, Chang Ya-Jen, Pichavant Muriel, Shore Stephanie A, Fitzgerald Katherine A, Iwakura Yoichiro, Israel Elliot, Bolger Kenneth, Faul John, DeKruyff Rosemarie H, Umetsu Dale T
Nat. Med. 2014 1;20:54-61

2014

2013

Intronic SH2D1A mutation with impaired SAP expression and agammaglobulinemia.
Recher Mike, Fried Ari J, Massaad Michel J, Kim Hye Young, Rizzini Michela, Frugoni Francesco, Walter Jolan E, Mathew Divij, Eibel Hermann, Hess Christoph, Giliani Silvia, Umetsu Dale T, Notarangelo Luigi D, Geha Raif S
Clin. Immunol. 2013 2;146:84-9

2013

T-cell immunoglobulin and mucin domain 1 deficiency eliminates airway hyperreactivity triggered by the recognition of airway cell death.
Kim Hye Young, Chang Ya-Jen, Chuang Ya-Ting, Lee Hyun-Hee, Kasahara David I, Martin Thomas, Hsu Joyce T, Savage Paul B, Shore Stephanie A, Freeman Gordon J, Dekruyff Rosemarie H, Umetsu Dale T
J. Allergy Clin. Immunol. 2013 8;132:414-25.e6

2013

Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity.
Albacker Lee A, Chaudhary Vinod, Chang Ya-Jen, Kim Hye Young, Chuang Ya-Ting, Pichavant Muriel, DeKruyff Rosemarie H, Savage Paul B, Umetsu Dale T
Nat. Med. 2013 10;19:1297-304

2012

Pulmonary inflammation induced by subacute ozone is augmented in adiponectin-deficient mice: role of IL-17A.
Kasahara David I, Kim Hye Y, Williams Alison S, Verbout Norah G, Tran Jennifer, Si Huiqing, Wurmbrand Allison P, Jastrab Jordan, Hug Christopher, Umetsu Dale T, Shore Stephanie A
J. Immunol. 2012 5;188:4558-67

2012

Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity.
Kim Hye Young, Chang Ya-Jen, Subramanian Srividya, Lee Hyun-Hee, Albacker Lee A, Matangkasombut Ponpan, Savage Paul B, McKenzie Andrew N J, Smith Dirk E, Rottman James B, DeKruyff Rosemarie H, Umetsu Dale T
J. Allergy Clin. Immunol. 2012 1;129:216-27.e1-

2012

Extrathymically generated regulatory T cells control mucosal TH2 inflammation.
Josefowicz Steven Z, Niec Rachel E, Kim Hye Young, Treuting Piper, Chinen Takatoshi, Zheng Ye, Umetsu Dale T, Rudensky Alexander Y
Nature 2012 2;482:395-9

2012

2011

Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity.
Chang Ya-Jen, Kim Hye Young, Albacker Lee A, Lee Hyun Hee, Baumgarth Nicole, Akira Shizuo, Savage Paul B, Endo Shin, Yamamura Takashi, Maaskant Janneke, Kitano Naoki, Singh Abel, Bhatt Apoorva, Besra Gurdyal S, van den Elzen Peter, Appelmelk Ben, Franck Richard W, Chen Guangwu, DeKruyff Rosemarie H, Shimamura Michio, Illarionov Petr, Umetsu Dale T
J. Clin. Invest. 2011 1;121:57-69

2011

A polymorphism in TIM1 is associated with susceptibility to severe hepatitis A virus infection in humans.
Kim Hye Young, Eyheramonho María Belén, Pichavant Muriel, Gonzalez Cambaceres Carlos, Matangkasombut Ponpan, Cervio Guillermo, Kuperman Silvina, Moreiro Rita, Konduru Krishnamurthy, Manangeeswaran Mohanraj, Freeman Gordon J, Kaplan Gerardo G, DeKruyff Rosemarie H, Umetsu Dale T, Rosenzweig Sergio D
J. Clin. Invest. 2011 3;121:1111-8

2011

nnate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity.
Chang Ya-Jen, Kim Hye Young, Albacker Lee A, Baumgarth Nicole, McKenzie Andrew N J, Smith Dirk E, Dekruyff Rosemarie H, Umetsu Dale T
Nat. Immunol. 2011 5;12:631-8

2010

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