Laboratory of Mucosal Immunology

Publications

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Publications

2018

Sodium chloride inhibits IFN-γ, but not IL-4, production by invariant NKT cells.
Jeong Dongjin, Kim Hye Young, Chung Doo Hyun
J. Leukoc. Biol. 2018 1;103:99-106

2018

The invariant natural killer T cell-mediated chemokine X-C motif chemokine ligand 1-X-C motif chemokine receptor 1 axis promotes allergic airway hyperresponsiveness by recruiting CD103dendritic cells.
Woo Yeon Duk, Koh Jaemoon, Kang Hye-Ryun, Kim Hye Young, Chung Doo Hyun
J. Allergy Clin. Immunol. 2018;142:1781-1792

2017

Palmitate inhibits arthritis by inducing t-bet and gata-3 mRNA degradation in iNKT cells via IRE1α-dependent decay.
Ko Jae Sung, Koh Jae Moon, So Jae-Seon, Jeon Yoon Kyung, Kim Hye Young, Chung Doo Hyun
Sci Rep 2017 11;7:14940

2017

Functional Defects in Type 3 Innate Lymphoid Cells and Classical Monocytes in a Patient with Hyper-IgE Syndrome.
Chang Yuna, Kang Sung-Yoon, Kim Jihyun, Kang Hye-Ryun, Kim Hye Young
Immune Netw 2017 10;17:352-364

2017

Cytosolic Pellino-1-Mediated K63-Linked Ubiquitination of IRF5 in M1 Macrophages Regulates Glucose Intolerance in Obesity.
Kim Donghyun, Lee Ho, Koh Jaemoon, Ko Jae Sung, Yoon Bo Ruem, Jeon Yoon Kyung, Cho Young Min, Kim Tae Han, Suh Yun-Suhk, Lee Hyuk-Joon, Yang Han-Kwang, Park Kyong Soo, Kim Hye Young, Lee Chang Woo, Lee Won-Woo, Chung Doo Hyun
Cell Rep 2017 7;20:832-845

2017

Resveratrol in Asthma: A French Paradox?
Kim Hye Young
Allergy Asthma Immunol Res 2017 1;9:1-2

2017

IL-23 secreted by bronchial epithelial cells contributes to allergic sensitization in asthma model: role of IL-23 secreted by bronchial epithelial cells.
Lee Hyun Seung, Park Da-Eun, Lee Ji-Won, Chang Yuna, Kim Hye Young, Song Woo-Jung, Kang Hye-Ryun, Park Heung-Woo, Chang Yoon-Seok, Cho Sang-Heon
Am. J. Physiol. Lung Cell Mol. Physiol. 2017 1;312:L13-L21

2016

Innate lymphoid cells in asthma: Will they take your breath away?
Kim Hye Young, Umetsu Dale T, Dekruyff Rosemarie H
Eur. J. Immunol. 2016 4;46:795-806

2015

Thalidomide inhibits alternative activation of macrophages in vivo and in vitro: a potential mechanism of anti-asthmatic effect of thalidomide.
Lee Hyun Seung, Kwon Hyouk-Soo, Park Da-Eun, Woo Yeon Duk, Kim Hye Young, Kim Hang-Rae, Cho Sang-Heon, Min Kyung-Up, Kang Hye-Ryun, Chang Yoon-Seok
PLoS ONE 2015 ;10:e0123094

2014

Pivotal role of IL-6 in the hyperinflammatory responses to subacute ozone in adiponectin-deficient mice.
Kasahara David I, Kim Hye Y, Mathews Joel A, Verbout Norah G, Williams Alison S, Wurmbrand Allison P, Ninin Fernanda M C, Neto Felippe L, Benedito Leandro A P, Hug Christopher, Umetsu Dale T, Shore Stephanie A
Am. J. Physiol. Lung Cell Mol. Physiol. 2014 3;306:L508-20

2014

Two distinct domains of Flo8 activator mediates its role in transcriptional activation and the physical interaction with Mss11.
Kim Hye Young, Lee Sung Bae, Kang Hyen Sam, Oh Goo Taeg, Kim TaeSoo
Biochem. Biophys. Res. Commun. 2014 6;449:202-7

2014

Innate lymphoid cells and asthma.
Yu Sanhong, Kim Hye Young, Chang Ya-Jen, DeKruyff Rosemarie H, Umetsu Dale T
J. Allergy Clin. Immunol. 2014 4;133:943-50; qu

2014

Innate immunity in the lung regulates the development of asthma.
DeKruyff Rosemarie H, Yu Sanhong, Kim Hye Young, Umetsu Dale T
Immunol. Rev. 2014 7;260:235-48

2014

Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.
Kim Hye Young, Lee Hyun Jun, Chang Ya-Jen, Pichavant Muriel, Shore Stephanie A, Fitzgerald Katherine A, Iwakura Yoichiro, Israel Elliot, Bolger Kenneth, Faul John, DeKruyff Rosemarie H, Umetsu Dale T
Nat. Med. 2014 1;20:54-61

2014

The roles of innate lymphoid cells in the development of asthma.
Woo Yeonduk, Jeong Dongjin, Chung Doo Hyun, Kim Hye Young
Immune Netw 2014 8;14:171-81

2013

Intronic SH2D1A mutation with impaired SAP expression and agammaglobulinemia.
Recher Mike, Fried Ari J, Massaad Michel J, Kim Hye Young, Rizzini Michela, Frugoni Francesco, Walter Jolan E, Mathew Divij, Eibel Hermann, Hess Christoph, Giliani Silvia, Umetsu Dale T, Notarangelo Luigi D, Geha Raif S
Clin. Immunol. 2013 2;146:84-9

2013

T-cell immunoglobulin and mucin domain 1 deficiency eliminates airway hyperreactivity triggered by the recognition of airway cell death.
Kim Hye Young, Chang Ya-Jen, Chuang Ya-Ting, Lee Hyun-Hee, Kasahara David I, Martin Thomas, Hsu Joyce T, Savage Paul B, Shore Stephanie A, Freeman Gordon J, Dekruyff Rosemarie H, Umetsu Dale T
J. Allergy Clin. Immunol. 2013 8;132:414-25.e6

2013

Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity.
Albacker Lee A, Chaudhary Vinod, Chang Ya-Jen, Kim Hye Young, Chuang Ya-Ting, Pichavant Muriel, DeKruyff Rosemarie H, Savage Paul B, Umetsu Dale T
Nat. Med. 2013 10;19:1297-304

2012

Pulmonary inflammation induced by subacute ozone is augmented in adiponectin-deficient mice: role of IL-17A.
Kasahara David I, Kim Hye Y, Williams Alison S, Verbout Norah G, Tran Jennifer, Si Huiqing, Wurmbrand Allison P, Jastrab Jordan, Hug Christopher, Umetsu Dale T, Shore Stephanie A
J. Immunol. 2012 5;188:4558-67

2012

Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity.
Kim Hye Young, Chang Ya-Jen, Subramanian Srividya, Lee Hyun-Hee, Albacker Lee A, Matangkasombut Ponpan, Savage Paul B, McKenzie Andrew N J, Smith Dirk E, Rottman James B, DeKruyff Rosemarie H, Umetsu Dale T
J. Allergy Clin. Immunol. 2012 1;129:216-27.e1-

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